GenaMox

Composition

Each ml contains:

• Amoxicillin trihydrate (equivalent to amoxicillin) …… 150 mg

• Gentamicin (as sulfate) ……………………………………… 40 mg

• Excipients …………………………………………………………… q.s. to 1 ml

Description

Amoxicillin 15% & Gentamicin 4% Injection is a broad-spectrum injectable antibiotic combination intended for the treatment of systemic bacterial infections in livestock.
The formulation combines the cell wall–inhibiting action of amoxicillin with the potent bactericidal activity of gentamicin, providing effective coverage against a wide range of Gram-positive and Gram-negative pathogens.

Mode of Action

• Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial cell lysis.

• Gentamicin inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, resulting in rapid bacterial death.

The combination produces a synergistic antibacterial effect, especially in severe and mixed infections.

Indications

Treatment of infections caused by susceptible organisms, including:

• Respiratory tract infections

• Pneumonia and bronchopneumonia

• Septicemia

• Colibacillosis (E. coli)

• Salmonellosis

• Pasteurellosis

• Metritis

• Mastitis

• Urinary tract infections

• Skin and soft tissue infections

• Mixed Gram-positive and Gram-negative bacterial infections

Dosage & Administration

• Route: Intramuscular (IM) or Subcutaneous (SC)

• Dosage:
  As directed by the veterinarian according to species, body weight, and severity of infection.

• Treatment may be repeated if necessary under veterinary supervision.

Target Species

• Cattle

• Sheep

• Goats

• Calves

• Other susceptible livestock

Contraindications

• Hypersensitivity to penicillins, aminoglycosides, or any excipients

• Animals with severe renal impairment

Adverse Reactions

• Local reactions at the injection site

• Allergic reactions (rare)
  If adverse effects occur, discontinue treatment and consult a veterinarian.

Withdrawal Period

• Meat: As per local veterinary regulations

• Milk: As per local veterinary regulations

Storage

• Store below 25°C

• Protect from light and freezing

• Shake well before use

• Keep vial tightly closed

Precautions

• For veterinary use only

• Do not exceed recommended dosage

• Use with caution in animals with impaired renal function

• Observe withdrawal periods strictly

Presentation

• Injectable suspension

• Vials: 50 ml – 100 ml