GENADEX®

Dexamethasone Injection
For Veterinary Use Only

COMPOSITION

Each mL contains:
Dexamethasone ……………………………………… 2 mg
Excipients ………………………………………… q.s. to 1 mL

PHARMACOLOGICAL CLASS

Corticosteroid (glucocorticoid) – anti-inflammatory, anti-allergic, and immunosuppressive agent.

INDICATIONS

GENADEX® is indicated for the treatment of conditions requiring rapid corticosteroid action, including:

• Acute and chronic inflammatory conditions

• Allergic reactions and anaphylaxis (supportive therapy)

• Shock and stress-related conditions

• Musculoskeletal disorders

• Respiratory inflammatory conditions

• Edema

• Supportive treatment in ketosis and parturient paresis (as directed)

in cattle, sheep, goats, camels, horses, dogs, and cats, under veterinary supervision.

DOSAGE AND ADMINISTRATION

For intramuscular or intravenous injection, as advised by a veterinarian.

• Large animals (cattle, camels, horses):
  0.02 – 0.05 mg dexamethasone per kg body weight

• Sheep and goats:
  0.05 – 0.1 mg per kg body weight

• Dogs and cats:
  0.1 – 0.2 mg per kg body weight

Dosage and duration depend on the condition and clinical response.

CONTRAINDICATIONS

• Hypersensitivity to dexamethasone or other corticosteroids

• Viral infections (unless combined with appropriate therapy)

• Gastrointestinal ulcers

• Diabetes mellitus

• Advanced pregnancy (may induce parturition)

ADVERSE REACTIONS

• Immunosuppression with prolonged use

• Polyuria, polydipsia, and polyphagia

• Delayed wound healing

• Risk of abortion when used during late pregnancy

WITHDRAWAL PERIOD

• Meat: 8 days

• Milk: 72 hours

(Subject to local regulatory requirements.)

PRECAUTIONS & WARNINGS

• Use the lowest effective dose for the shortest duration

• Do not discontinue prolonged therapy abruptly

• Avoid concurrent use with NSAIDs

• Use with caution in stressed or debilitated animals

STORAGE

• Store below 25°C

• Protect from light

• Do not freeze

• Keep container tightly closed

• Keep out of reach of children

PRESENTATION

Glass vial containing 100 mL sterile injectable solution.

MANUFACTURED BY

NORWICH ANIMAL HEALTH