COLINOR® 2400 Oral Liquid

COLINOR® 2400 Oral Liquid

Colistin Sulfate Oral Antibacterial Solution


Composition

Each ml contains:
Colistin sulfate ................................. 2,400,000 IU
Excipients ............................................. q.s. to 1 ml


Pharmaceutical Form

Oral liquid solution for veterinary use.


Therapeutic Class

Polymyxin antibiotic (Gram-negative antibacterial).


Indications

COLINOR® 2400 Oral Liquid is indicated for the treatment of gastrointestinal infections caused by colistin-sensitive Gram-negative bacteria, including:

  • Colibacillosis (E. coli)

  • Salmonellosis

  • Enteritis

  • Bacterial diarrhea

  • Secondary intestinal infections


Target Species

  • Poultry (broilers & breeders)

  • Calves

  • Lambs & kids


Mechanism of Action

Colistin acts by disrupting the cell membrane of Gram-negative bacteria, leading to leakage of cellular contents and rapid bacterial death.
It is particularly effective against E. coli and other enteric pathogens.


Dosage & Administration

For oral administration via drinking water or direct oral dosing.

Poultry

  • 75,000–150,000 IU/kg body weight/day
    for 3–5 consecutive days

Calves, Sheep & Goats

  • 100,000 IU/kg body weight/day
    for 3–5 days

📌 Ensure medicated water is the only source of drinking water.
📌 Shake well before use.


Contraindications

  • Hypersensitivity to colistin

  • Do not use in animals with severe renal impairment

  • Avoid prolonged or unnecessary use


Side Effects

  • Generally well tolerated

  • Rare digestive disturbances

  • Overdose may increase risk of nephrotoxicity


Withdrawal Period

(Indicative – subject to local regulations)

  • Meat:
    Poultry & ruminants: 1–3 days

  • Eggs:
    0 days


Special Warnings

  • Use only when bacterial sensitivity is expected

  • Avoid misuse to reduce antimicrobial resistance

  • Observe antimicrobial stewardship principles


Storage Conditions

  • Store below 25°C

  • Protect from direct sunlight

  • Do not freeze

  • Keep out of reach of children


Shelf Life

  • 24 months from date of manufacture

  • Use within 28 days after first opening


Presentation

  • 100 ml bottle

  • 250 ml bottle

  • 500 ml bottle

  • 1 Liter bottle